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  • Writer's pictureRoger Schechter, MD

How do Exosomes enhance Radiofrequency Microneedling?

Traditionally, the aesthetics industry has utilized products to artificially restore beauty made of up toxins and fillers.





While consumer preference continues to trend towards natural products for skin and hair treatments, the regenerative aesthetics market does not have that many reliable and consistent regenerative solutions that leverage our own body regenerative capabilities.

For this reason, Radiofrequency (RF) microneedling is becoming one of the most highly requested aesthetic treatments.


This treatment, coupled with exosomes as a post-procedure application, is providing aesthetic physicians with a powerful anti-aging tool.


How does RF Microneedling work?

RF microneedling provides the power of two treatments in one.


Microneedling uses a fine needle to create micro wounds, or channels, in the skin. This triggers the production of capillaries, elastin, and collagen.


The needle releases radiofrequency into the channels, causing additional damage. The RF energy heats up the underlying skin layers, causing skin tightening and stimulating collagen and elastin production.


This RF energy is delivered deeply into the skin layers, producing better and faster results.


What are exosomes?

Exosomes are tiny vesicles secreted by your cells containing proteins and nucleic acids. They are responsible for cell-to-cell communication, delivering the information and building blocks to regenerate.


As we age, our skin’s ability to repair damaged cells and maintain collagen synthesis is diminished.


Exosomes facilitate the exchange of mRNA and miRNA, which deliver instructions to the recipient cells.


In addition, exosomes deliver the materials needed to carry out the instructions, including cytokines, growth factors, and proteins like keratin, which helps form your epidermis.

Clinical studies have shown exosomes to be effective for things like hair restoration and for boosting collagen production.


How do Exosomes enhance results for RF?

Aesthetic physicians are increasingly using exosomes as a companion product to enhance the results from RF microneedling, drastically expediting healing and improving collagen-producing effects.


By applying exosomes directly to the tissue, the long cellular division process is bypassed, instead going straight to the replenishment and regeneration of the treatment area. Done post-RF microneedling procedure allows these exosomes to reach the deeper skin layers more easily so they can promote skin repair more rapidly.


Additionally, exosomes can help reduce post-procedure downtime, as well as the redness, swelling, and burning that often accompany RF treatments.


According to Dr. Robert Schechter, Chief Medical Officer at Exocel Bio, “Typically, the downtime associated with energy-based devices is reduced by up to 80%"



About Exocel

Selecting a high-quality exosome product is important as results can vary dependent on the purity, concentration, and molecules within the product.


Exovex strives to be the leader in nanoparticle technology and methodology using a complex manufacturing process utilizing 3rd party testing to ensure purity and standardization of their product.


Exovex Exosomes have been shown to increase elastin up to 300% and skin collagen up to 6-fold in the treated areas.


If your practice is looking to add exosome nanoparticle technology, contact Exovex on 858.255.4499 to find out how exosomes can add value to your patients and your practice.




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