Roger Schechter, MD
No Blood Lost with Exosomes
Platelet Rich Plasma (PRP) has long been used for a variety of aesthetic and regenerative treatments. PRP has had mixed success in it’s use to treat joints, hair loss, and in skin rejuvenation. There are several disadvantages to this approach.
PRP relies on drawing vials of the patient’s own blood. Many patients are uncomfortable with this process and can experience pain or infection because of the blood draw. Treatment response is often mixed for different reasons. The PRP is only as good as the age of the patient, meaning therapies performed in younger patients are likely to be more successful than in older patients as overall health and cell integrity declines. PRP is not always effective and appears to have fewer benefits than exosomes in treating a variety of conditions.
Increasingly, patients are valuing their time and looking for effective and efficient treatment options. Blood draws for PRP therapy mean the blood must be drawn then spun in a centrifuge taking about 15 minutes for this process to occur. Add to this the redness that patients often experience, down time can be a day or two due to this inflammation.
The benefits of using exosomes for rejuvenation therapies are numerous when compared to PRP treatments. Exosomes have demonstrated promising results in many patients for treatments that include hair loss, aesthetics, wound repair, and treatment of surgical incisions.
Exosomes are derived from placental mesenchymal stem cells (pMSCs). They are nanoparticles which are released and act as messengers for most every cell in the body. The biological function of these nanoparticle is determined by the molecules that exist on its surface or interior and act upon specific physiological or environmental cues. Exosomes carry miRNA, mRNA and growth factors to recipient cells. These biologicals are free of cellular material and derived from placental stem cells meaning the product has a greater capacity for rejuvenation due to the youth of the cell origins.
Research is still being performed on this exciting treatment as science continues to evolve and understand more about cell communication. Exosomes have shown significant reduction in downtime from procedures due to the almost instant anti-inflammatory effect. Furthermore, the absence of cellular materials means there is no rejection of the product, having a high safety profile.
Exosomes are available for licensed medical professionals for in-office use. They arrive to your clinic cryogenically-frozen, where the provider simply needs to thaw the product out and use it as a topical application, without the need for any bulky equipment.
With no up-front cost and a low unit cost, Exovex is quickly becoming the preferred option for medical aesthetic providers.