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  • Writer's pictureRoger Schechter, MD

The Future of Longevity Medicine

An Interview with Sandra Kaufmann, MD Longevity Medicine Expert

Dr. Sandra Kaufmann is a renowned expert in the field of longevity medicine, having published two books on the subject: Why We Age and How to Stop It and Aging Solutions. She has dedicated her research to understanding the mechanisms of aging and developing novel interventions to promote healthy aging and extend human lifespan.

Although her specialty is Pediatric Anesthesiology, Dr. Kaufmann’s background in cell biology, pharmacology, and physiology sparked her interest in anti-aging, which has become her focus.

In this interview, we have the privilege of speaking with Dr. Kaufmann about cellular health, her anti-aging protocol, and her thoughts on the future of exosomes in longevity medicine.

Why do cells age?

Cells age for very specific reasons. I like to classify these into the seven tenets of aging, which are as follows:

  1. DNA alterations (telomere attrition, epigenetics)

  2. Mitochondrial failure

  3. Pathways (Sirtuins, AMP Kinase, mTOR)

  4. Quality control (DNA & Protein repair mechanisms and Autophagy)

  5. Immune and inflammatory systems

  6. Individual cell needs (Senescent, Stem cells)

  7. Waste management (Glycation, lipofuscin)

How did you devise the Kaufmann Rating System?

The rating system was designed to reflect the idea that different agents could simultaneously decelerate aging in several categories, and that there were various levels of efficacy or evidence involved. Thus, the ratings can be used by the consumer to more scientifically understand exactly what a particular agent does, as well as more readily create a comprehensive longevity protocol.

What role do you see biologics playing in longevity medicine in the future?

The science of longevity is the absolute future of medicine and I like to think that the longevity pyramid is an excellent way to organize these strategies. Thus, there are things that can be done daily, which include an appropriate diet and adequate exercise in addition to daily supplements, adjuvants and medications. Peptides and light strategies are very useful tools.

Less frequently, but equally if not even more important, are the biologics. My favorite strategy is monthly intravenous exosome injection. Patients experience a reduction in systemic inflammation, improved healing, improved libido, and a significant boost in energy. At a very reasonable cost and very little risk, I believe this to be almost mandatory on the longevity path.

Why do you see exosomes as a superior alternative to stem cells?

Stem cells are fantastic in terms of longevity, however there are limitations. Exogenous stem cells are currently not available in this country. Meanwhile, autologous stem cells are only as healthy as the person they which they come. Exosomes, on the other hand, constitute up to 80% of the benefits seen with stem cells and are readily available in addition to being less expensive.

How can people learn more about longevity and the Kaufmann Protocol?

I would suggest curious folks turn to the website: to get started. The site offers a simplified explanation of what the protocol is and how to get started. The next step is reading the books, The Kaufmann Protocol: Why we age and How to stop it, followed by Aging Solutions. Lastly, I am personally available at

Dr. Kaufmann’s books are available to purchase on Amazon.

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