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  • Writer's pictureRoger Schechter, MD

Which Regenerative Product is Best?

Updated: Jul 28, 2022

With the plethora of products that are pouring into the regenerative market, it can be hard to know where to start. Which product to use, for what, and what’s the difference?


Secretomes have become a strong player in this market due to the immediate benefits in reducing inflammation as well as having a variety of applications for use. Secretomes contain nanovesicles that can help with anti-aging and hair regrowth. They are a rich source of growth factors, peptides, and mRNA which target and repair damaged tissue at sites of inflammation. The quality of secretomes is vital to ensure efficacy as well as absence of reactions.

Exovex is produced using the highest quality of secretomes available for topical use post aesthetic procedure. Their manufacturing process ensures that the nanovesicles remain intact and exclude the presence of DNA and cellular material. Use of the intact nanovesicle enables a full mechanism of action in cells and provides the best results. Exovex secretomes are derived from the chorion layer of the placenta. The nanovesicles are selected based on specific pMCS and then filtered, concentrated, counted, and tested. The product is also third party tested to ensure quality. Exovex prides itself on the quality of its product and the results patients experience.

Platelet Rich Plasma (PRP) has been used since the 1980’s and is reliant on the source of the platelets. Platelets are extracted from a patient’s own blood via a blood draw. The efficacy of PRP diminishes with patient age and condition, resulting in inconsistent and variable results. There are very few growth factors present and almost no exosomes, limiting the benefits to the patient. Patients also experience inflammation because of the treatment, increasing downtime and discomfort.

Benev contains Hyaluronic Acid which creates instant results but are short lived. The product is derived from lyophilized exosomes that are ruptured resulting in a damaged exosome crossing the cell membrane. In this state, the exosome is less effective than if it were intact. This product is an expensive HA with some growth factors that often results in some placebo effect.

Kimera is a low concentration and potency exosome product that is extremely overpriced. Users of the product even seems to complain about the inconsistency of results. Companies like Kimera have also been marketing the use of exosomes to treat a variety of conditions that are unapproved as well as being under scrutiny for legal violations.

Selecting the best product for your patient is an important decision. Efficacy and down time for the patient, and reputation of the company you are working with are upfront considerations. With so many players in the market, choose a vendor who can stand behind their product ethically and confidently.

Exocel Bio strives to be the leader in the aesthetic industry though use of nanoparticle technology and methodology that is rooted in sound facts and science. Patient safety is at the forefront of the company culture.

To find out more about Exovex:


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