EXOVEX are the most comprehensively characterized exosomes on the market, using the latest nucleic acid sequencing techniques and human peptide analysis. This demonstrates that EXOVEX contain a diverse payload of functional proteins including: collagens, extracellular matrix proteins, cytokines, growth factors and enzymes.
Through qualitative analysis, EXOVEX exosomes are shown to envelop hundreds of growth factors and anti-inflammatory proteins, including: BMP-5, GDF-15, OPG, SCF, TGFb3, VEGF, IL-1ra, IL-6, IL-10, MCP-1, MIP-1b, PDGF-BB. TIMP-1, TIMP-2, TNF RI
EXOVEX exosomes are tested to be completely free of any DNA. They are quantitatively characterized via
Nanoparticle Tracking Analysis and Next Generation Sequencing (NGS) to fully measure:
Particle size and concentration All RNA species
All Functional Molecules
This meticulous process assures that EXOVEX are the most comprehensively screened, safe and effective exosomes in the world.
EXOVEX are manufactured using Mesenchymal Stem Cells (MSCs), harvested from a single placental chorion per each batch of exosomes. MSCs are specifically selected early in the process to ensure efficient production of uncontaminated high-fidelity and functional cells. All donor tissue is screened for pathogens and tested to insure that it is negative for communicable diseases, plus each EXOVEX vial is confirmed to be contaminant free. Only Exosomes less than 100 nanometers (0.1 Microns) in diameter are collected, utilizing ultrafiltration to ensure exclusion of bacteria, Mycoplasma and fungi.
Utilizing light scattering fluorescent staining flowtometry insures that EXOVEX have a 10-fold greater exosome count per milliliter, compared with those produced by our closest competitors.