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Manufacturing

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Exocel Bio employs an innovative proprietary incubation medium and a stringent nine step GXP process, to produce the highest potency and safety profile of all the EVs currently available. Exovex envelops growth factor know to help reduce the signs of gaining of the skin and to enhance the healthy appearance of both the scalp and hair.

Differentiators

  • Proprietary Medium

  • Potent and Precision Growth Factors

  • Free of DNA

  • Thorough Screening

  • Comprehensive Characterization

  • High Potency

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Our Quantity is Quality

Exovex are the most comprehensively characterized EVs on the market, using the latest nucleic acid sequencing techniques and human peptide analysis.

This demonstrates that Exovex contain a diverse payload of functional proteins including collagens, extracellular matrix proteins, cytokines, growth factors and enzymes.


Through qualitative analysis, Exovex is shown to envelop hundreds of growth factors and anti-inflammatory proteins, including: BMP-5, GDF-15, OPG, SCF, TGFb3, VEGF, IL-1ra, IL-6, IL-10, MCP-1, MIP-1b, PDGF-BB. TIMP-1, TIMP-2, TNF RI

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Thorough Screening

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EXOVEX is tested to be completely free of any DNA. They are quantitatively characterized via Nanoparticle Tracking Analysis and Next Generation Sequencing (NGS) to fully measure:

  • Particle size and concentration

  • All RNA species

  • All Functional Molecules

This meticulous process assures that EXOVEX is the most comprehensively screened, safe and effective EVs in the world.

High Potency

Exovex is manufactured using Mesenchymal Stem Cells (MSCs), harvested from a single placental chorion per each batch of EVs. 

 

MSCs are specifically selected early in the process to ensure efficient production of uncontaminated high-fidelity and functional cells. All donor tissue is screened for pathogens and tested to insure that it is negative for communicable diseases, plus each Exovex vial is confirmed to be contaminant free. Only EVs less than 100 nanometers (0.1 Microns) in diameter are collected, utilizing ultrafiltration to ensure exclusion of bacteria, Mycoplasma and fungi.
Utilizing light scattering fluorescent staining flowtometry insures that Exovex have a 10-fold greater EVs count per milliliter, compared with those produced by our closest competitors.

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