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  • Writer's pictureRoger Schechter, MD

Exploring the Potential of Chorion Layer: A Rich Source of Stem Cells

The regenerative potential of stem cells derived from the chorion layer of the developing fetus has garnered increasing interest in the field of regenerative medicine. A study published by the NIH shed light on the exceptional attributes of fetal mesenchymal stem cells (MSCs) that are derived from the chorion layer.

Abundance and Accessibility of Fetal MSCs

The study confirms that the chorion layer serves as an abundant and accessible source of fetal MSCs. Researchers have successfully isolated and expanded MSCs from this membrane, providing a valuable and readily available cell population for therapeutic applications. The abundance and accessibility of fetal MSCs from the chorion layer offer practical advantages in terms of research, scalability, and potential clinical translation.

The chorion layer, consisting of the chorionic plate and the chorionic villi, provides a rich reservoir of stem cells. What makes it even more appealing is its easy accessibility. Following childbirth, the chorionic membrane is typically discarded as medical waste. However, with proper protocols in place, this otherwise discarded tissue can be salvaged and utilized for its regenerative properties, offering a non-invasive and abundant source of stem cells.

Unique Properties of Fetal MSCs

The study highlights the unique properties of fetal MSCs derived from the chorion layer, contributing to their superiority as a stem cell source. These cells exhibit enhanced proliferation and differentiation capacities compared to adult-derived MSCs. Additionally, the chorion-derived fetal MSCs display potent immunomodulatory properties, reducing inflammatory responses and promoting tissue repair. Such attributes make them highly desirable for various regenerative medicine applications.

Therapeutic Potential

The study emphasizes the therapeutic potential chorion-derived fetal MSCs. They can enhance tissue regeneration, stimulate angiogenesis, and exert anti-inflammatory effects. Additionally, chorion-derived fetal MSCs have shown promise in promoting neuroprotection and tissue repair in various disease models.

Immunomodulatory Properties

Chorionic membrane-derived MSCs have displayed remarkable immunomodulatory properties. These cells possess the ability to regulate the immune response within the body. This characteristic is particularly significant for potential applications in treating autoimmune disorders and in tissue transplantation. By modulating the immune system's response, chorion-derived MSCs hold immense promise for mitigating inflammation and promoting tissue repair and regeneration.


The chorion layer, a remarkable source of fetal MSCs, offers unparalleled advantages in regenerative medicine. The abundant supply, accessibility, enhanced proliferation and expansion capacity, immunomodulatory properties, and low risk of rejection associated with chorion-derived fetal MSCs position them as the optimal choice for various therapeutic applications.

About Exovex

Exocel Bio is the manufacturer of Exovex Exosomes, a potent blend of precision growth factors, peptides, cytokines, and mRNA that target damaged skin and hair cellular structures topically by providing the nutrients and resources necessary to facilitate the repair of cells.

Exovex Exosomes are derived from the chorion layer of placenta donated from cesarean births.

Exovex Exosomes are for topical use only. The FDA has not approved Exosomes for systematic use or injection.

Contact us today to add this powerful treatment to your clinic.

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